NMR Facility

Department of Chemistry University of Oxford

Factor-Inhibiting Hypoxia-Inducible Factor (FIH) Catalyses the Post-translational Hydroxylation of Histidinyl Residues within Ankyrin Repeat Domains
Ming Yang, Rasheduzzaman Chowdhury, Wei Ge, Refaat B. Hamed, Michael A. McDonough, Timothy D. W. Claridge, Benedikt M. Kessler, Matthew E. Cockman, Peter J. Ratcliffe and Christopher J. Schofield
FEBS Lett., (2011), 278, 1086-1097

Dimeric Self-Association of an Isophthalamide Macrocycle in Solution and the Solid State
Christopher J. Serpell, Owen Thomas, Barbara Odell, Timothy D. W. Claridge, Ricky Chall, Amber L. Thompson, and Paul D. Beer
Cryst. Eng. Comm., (2011), 13, 4586-4591

Separating electrophilicity and lewis acidity: the synthesis, characterization, and electrochemistry of the electron deficient tris(aryl)boranes B(C6F5)3-n(C6Cl5)n (n = 1-3)
Ashley, Andrew E.; Herrington, Thomas J.; Wildgoose, Gregory G.; Zaher, Hasna; Thompson, Amber L.; Rees, Nicholas H.; Kramer, Tobias; O'Hare, Dermot
J. Am. Chem. Soc. (2011), 133, 14727-14740

All-or-Nothing Cooperative Self-Assembly of an Annulene Sandwich
Johannes K. Sprafke, Barbara Odell, Timothy D. W. Claridge and Harry L. Anderson
Angew. Chem. Int. Ed. Engl., (2011), 50, 5572-5575

An approach to enzyme inhibition employing reversible boronate ester formation
Ivanhoe K. H. Leung, Tom Brown Jr, Christopher J. Schofield, Timothy D. W. Claridge.
Med. Chem. Comm., (2011),  2, 390-395

Dearomatisation of o-Xylene by P450BM3 (CYP102A1)
Whitehouse, Christopher J. C.; Rees, Nicholas H.; Bell, Stephen G.; Wong, Luet-Lok
Chem. Eur. J. (2011), 17, 6862-6868

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases
Refaat B. Hamed, J. Ruben Gomez-Castellanos, Armin Thalhammer, Daniel Harding, Christian Ducho, Timothy D. W. Claridge, and Christopher J. Schofield.
Nature Chem., (2011), 3, 365-371

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya-Min Tian, Lars Hillringhaus, Eleanor A. Bagg, Nathan R. Rose, Ivanhoe K.H. Leung, Xuan S. Li, Esther C.Y. Woon, Ming Yang, Michael A.McDonough, Oliver N. King, Ian J. Clifton, Robert J. Klose, Timothy D.W. Claridge, Peter J. Ratcliffe, Christopher J. Schofield & Akane Kawamura
EMBO Reports, (2011),  12, 463-469

New insights into the intercalation chemistry of Al(OH)3
Williams, Gareth R.; Moorhouse, Saul J.; Prior, Timothy J.; Fogg, Andrew M.; Rees, Nicholas H.; O'Hare, Dermot
Dalton Trans. (2011), 40, 6012-6022

The bis(hydrogenheptaphosphide)iron(II) dianion: a Zintl ion analogue of ferrocene?
Caroline M. Knapp, Joseph S. Large, Nicholas H. Rees and Jose M. Goicoechea
Chem. Commun., (2011), 47, 4111-4113

{Rh(PiBu3)2}+ Fragments Ligated to Arenes: From Benzene to Polyaromatic Hydrocarbons. Part I: An Experimental Approach
Woolf, Anthony; Chaplin, Adrian B.; McGrady, John E.; Alibadi, Muhsen A. M.; Rees, Nicholas; Draper, Sylvia; Murphy, Frances; Weller, Andrew S
Eur. J. Inorg. Chem. (2011), 10, 1614-1625

A systematic study of the solid state and solution phase conformational preferences of b-peptides derived from C(3)-alkyl substituted transpentacin derivatives
Elin Abraham, Timothy D.W. Claridge, Stephen G. Davies , Barbara Odell, Paul M. Roberts, Angela J. Russell, Andrew D. Smith, Lorna J. Smith, Helen R. Storr, Miles J. Sweet, Amber L. Thompson, James E. Thomson, George E. Tranter, David J. Watkin
Tetrahedron: Asymmetry, (2011), 22, 69-100

Asparagine and aspartate hydroxylation of the cytoskeletal Ankyrin family is catalysed by Factor-Inhibiting Hypoxia-Inducible Factor
Ming Yang, Wei Ge, Rasheduzzaman Chowdhury, Timothy D. W. Claridge, Holger B. Kramer, Bernhard Schmierer, Michael A. McDonough, Lingzhi Gong, Benedikt M. Kessler, Peter J. Ratcliffe, Mathew L. Coleman, and Christopher J. Schofield
J. Biol. Chem., (2011), 286, 7648-7660

The 2-Oxoglutarate Dependent Oxygenase JMJD6 Catalyses Oxidation of Lysine Residues to give 5S-Hydroxylysine Residues
Monica Mantri, Nikita D. Loik, Refaat B. Hamed, Timothy D. W. Claridge, James S. O. McCullagh, Christopher J. Schofield
ChemBioChem, (2011), 12, 531-534.

Tuning the cavity of cyclodextrins: altered sugar adaptors in protein pores
Wen-Wu Li, Timothy D.W. Claridge, Qiuhong Li, Mark R. Wormald, Benjamin G. Davis and Hagan Bayley
J. Am. Chem. Soc., (2011), 133, 1987-2001

Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444
Ma, Ming; Bell, Stephen G.; Yang, Wen; Hao, Yiming; Rees, Nicholas H.; Bartlam, Mark; Zhou, Weihong; Wong, Luet-Lok; Rao, Zihe
ChemBioChem, (2011), 12, 88-99

A versatile salt-metathesis route to heteroatomic clusters derived from phosphorus and arsenic Zintl anions
Knapp, Caroline M.; Large, Joseph S.; Rees, Nicholas H.; Goicoechea, Jose M.
Dalton Trans., (2011), 40, 735-745

Vernier Templating and Synthesis of a 12-Porphyrin Nano-ring
Melanie C. O’Sullivan, Johannes K. Sprafke, Dmitry V. Kondratuk, Corentin Rinfray, Timothy D. W. Claridge, Alex Saywell, Matthew O. Blunt, James N. O’Shea, Peter H. Beton, Marc Malfois & Harry L. Anderson.
Nature, (2011), 469, 72-75.