NMR Facility

Department of Chemistry University of Oxford

Reducing agent mediated non-enzymatic conversion of 2-oxoglutarate to succinate – implications for oxygenase assays.
Amjad Khan, Christopher J. Schofield, and Timothy D. W. Claridge, ChemBioChem, 2020, [DOI: 10.1002/cbic.202000185]

NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions–NMR waterLOGSY.
Carole J. R. Bataille, Terence H. Rabbitts, and Timothy D. Claridge, Bio-protocol 10(13): e3666. [DOI: 10.21769/BioProtoc.3666] 

Monitoring protein-metal binding by 19F NMR – Case study with the New Delhi metallo-β-lactamase 1.
Anna M. Rydzik, Jürgen Brem, Timothy D. W. Claridge, and Christopher J. Schofield, RSC Med. Chem., 2020,11, 387-391 [DOI: 10.1039/c9md00416e] 

Global Aromaticity at the Nanoscale
Michel Rickhaus, Michael Jirasek, Lara Tejerina, Henrik Gotfredsen, Martin D. Peeks, Renée Haver, Hua-Wei Jiang, Timothy D. W. Claridge, and Harry L. Anderson, Nat. Chem., 2020, 12, 236–241 [DOI: 10.1038/s41557-019-0398-3]

Studies on the Selectivity of Proline Hydroxylases Reveal New Substrates Including Bicycles
Tristan J. Smart, Refaat B. Hamed, Timothy D. W. Claridge, Christopher J. Schofield, Bioorganic Chemistry, 2020, 94 103386 [DOI: 10.1016/j.bioorg.2019.103386]