NMR Facility

Department of Chemistry University of Oxford

Bruker AVIIIHD 500

CRL high-field NMR lab. 00.086

This is a 2-channel instrument running TOPSPIN 3. It was upgraded to an AVIII HD console in July 2019. It is equipped with:

-16-position SampleExpress Lite robotic sample changer (not seen in photo below)

-5mm z-gradient broadband1H/19F-X multinuclear (BBFO) SMART probe (default probe).

-5mm z-gradient triple resonance inverse 1H/19F(13C) TXI probe.

-1mm z-gradient inverse 1H{13C, 15N} triple resonance TXI microprobe.

-BCU-I temperature regulation unit, with liquid nitrogen heat exchanger or evaporator for low-temperature work.

The BBFO probe allows us to collect both 1H-19F and 1H-X experiments and is used by default.

The 1mm microprobe is ideal for handling samples in the microgram (or even sub-microgram) range, most notably those from biosynthetic sources (although cryoprobes have largely replaced the need for this).

This instrument is used by the NMR service staff and by trained research chemists and operates in "hands-on" or fully automated modes.

This instrument is nicknamed the AVB500 although the formal model name is an AVIII HD 500 and should be listed as such in any publication.